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Evidence from large British cohort studies suggests that the combination of a large placenta and low birth weight is a strong independent risk factor for cardiovascular disease in adulthood.1 2 3 This important finding adds to the epidemiological evidence that intrauterine influences are relevant in the development of adult disease.4 5 6 Hypertension is the most important known risk factor for coronary artery disease.
Hypertension is significantly more common in people whose history includes a placenta disproportionately large for their birth weight–that is, those who had a high placental weight to birthweight ratio.1 Barker and colleagues formed a broad hypothesis that maternal undernutrition before and during pregnancy influences the relative growth rates of the fetus and the placenta,1 2 3 4 5 6 programming fetal metabolism and predisposing the person to hypertension in adulthood.
By clicking or navigating the site, you agree to allow our collection of information on and off Facebook through cookies.Main outcome measures: Placental weight, birth weight, and the ratio of placental weight to birth weight.Results: By multiple regression analysis the placental weight to birthweight ratio was significantly and positively associated with gestational age, female sex, Asian parentage, increasing maternal body mass index, increased maternal weight at booking, lower socioeconomic status, maternal anaemia, and increasing number of cigarettes smoked daily.The updated firmware (V3.12) will add a No-Fly Zone centered on the White House and extending for a 25 kilometer (15.5 mile) radius in all directions.This addition is part of DJI’s ongoing work with regulators to ensure safe flight, and is being included in a scheduled firmware update.
DJI is continuing to update its no fly zone list to include sensitive institutions and national borders in compliance with local regulations.